The Society for Immunotherapy of Cancer (SITC) published it's first clinical practice guideline (CPG) on immunotherapy for the treatment of Renal Cell Carcinoma in the Journal for ImmunoTherapy of Cancer on November 15, 2016.
With the many advancements in immuno-oncology for the treatment of renal cell carcinoma, the SITC Renal Cell Carcinoma expert panel reconvened, developed and published an updated CPG on immunotherapy for the treatment of Advanced Renal Cell Carcinoma in the Journal for ImmunoTherapy of Cancer on December 20, 2019.
SITC's Cancer Immunotherapy Guidelines program is a collection of CPGs developed by multi-disciplinary panels of experts who draw from their own practical experience as well as evidence in the published literature and clinical trial data to develop evidence- and consensus-based recommendations. SITC uses as a model the Institute of Medicine's 2011 "Standards for Developing Trustworthy Clinical Practice Guidelines" to ensure the recommendations are unbiased, transparent and balanced will aid oncologists in effective clinical decision-making concerning patient selection, toxicity management, response evaluation, and the sequencing or combination of therapies, among other topics.
The Advanced Renal Cell Carcinoma CPG was developed collaboratively through the efforts of an expert panel that convened to discuss the current therapeutic landscape. This CPG provides updated recommendations on the use of FDA-approved immune checkpoint inhibitors for advanced clear cell renal cell carcinoma, both as monotherapies and in combination regimens, with additional guidelines on patient selection, toxicity management, sequencing of therapies, and the treatment of non-clear cell pathology.