Marc S. Ernstoff, MD – Roswell Park Comprehensive Cancer Center
Igor Puzanov, MD, MSCI, FACP – Roswell Park Comprehensive Cancer Center
Caroline Robert, MD, PhD – Institut Gustave Roussy
Adi Diab, MD – The University of Texas MD Anderson Cancer Center
Peter Hersey, MD, PhD – University of Sydney
The Society for Immunotherapy of Cancer’s handbook, SITC's Guide to Managing Immunotherapy Toxicity, is a practical reference to managing side effects associated with U.S. Food and Drug Administration (FDA)-approved cancer immunotherapy treatments. Written by world-recognized thought leaders in the field of cancer immunotherapy, this text provides thorough coverage of the toxicity and management of adverse events experienced during treatment with immune checkpoint inhibitors.
Separated into two parts, Part I of the textbook contains chapter-based overviews of immune checkpoint inhibitors in the clinic, starting with anti-CTLA4 agents, anti-PD1/PD-L1 agents, and approved immunotherapeutic combinations. These chapters cover relevant mechanisms of action, indications, and toxicities seen while combating early, advanced, and metastatic stages in cancer patients. Part II is organized by the impact of toxicities on major organ sites throughout the body. It begins with general principles of immune-related toxicity management followed by chapters which focus on specific toxicities: rash and mucosal irritation, muscle and joint toxicity, diarrhea and colitis, pneumonitis, endocrine toxicities, neurological toxicities, cardiac toxicity, renal toxicity, hematologic toxicity, ocular toxicities and others. Each chapter provides guidance on how to assess and treat the toxicity and how to support the patient through acute and chronic effects. Part II concludes with a discussion on the management of special patient populations, such as patients with autoimmune disease and geriatric patients, as well as chapters on fatigue management and cost effectiveness.
This textbook is an essential resource for clinical oncologists, emergency physicians, hospitalists and other medical practitioners in both the academic and community hospital settings.
This handbook will also provide to clinicians:
- Strategies for treating high-risk patients facing acute or chronic side effects due to treatment with immunotherapy,
- Descriptions of the various clinical presentations observed during immunotherapy, and
- Tables which serve as a quick reference for the reader.
Purchase of this handbook includes access to the eBook for use on most mobile devices or computer. Click here to purchase this book today!