If you would like to place an ad on this page for a job opening you have at your organization, please download the agreement form (.DOC – .PDF) for the posting criteria and submit it, along with the job description, to firstname.lastname@example.org.
If you have any questions, please contact SITC at email@example.com or call 414-271-2456.
Prepare, compile and develop product registration data for the semi-regulated and regulated market.
Be well informed about eCTD, ACTD & country specific guidelines.
File regulatory documents within budget and timeline.
Interact with various departments/teams to collect documents required for dossier compilation on time as per regulatory norms.
Coordinate with manufacturing facilities for product samples, specifications, laboratory reports and
Interact with various external regulatory agencies.
Review the quality and analytical data as per the pharmacopoeia, specification, batch manufacturing
records, stability, finished product / packaging material data for the purpose of compilation of the dossier.
Review and manage applications for License and DMF.
Review and respond to technical queries related to product registration from FDA.
Maintain an online report of various submission status as well as queries at various stages of all
WORK EXPERIENCE REQUIREMENTS:
Experience in eCTD publishing (Required).
1 year pharmaceutical regulatory experience (Required).
1 year pharmaceutical product registration experience in non-US country (Required).
3-6 years experience in product registration in EU, TGA, FDA (Preferred).
Experience within a pharmaceutical/medical device organization and current Good Manufacturing
Practices (cGMPs)/Quality System (QS) Regulation is strongly preferred.
Proficient in computer skills with eCTD software, template creation for submission, Word/Excel/MS Office Suite and ERP systems.
Bachelor’s Degree in science, biotechnology, or related discipline.Interested applicants should send their resume and cover letters to firstname.lastname@example.org or apply by visiting our website at https://www.akronbiotech.com/.
Working for a small business is an opportunity to wear many hats and learn about all aspects of the business. While this position sits within the Research & Development Department, the ideal candidate will be extremely adaptable and comfortable taking on roles that relate to Quality Assurance, Finance, Regulatory Affairs, Manufacturing, Sales, Marketing, etc.
This position will be split between laboratory and office responsibilities.
Design and execute experiments with various primary immune cell types (e.g. NK cells, T cells, etc.) in
alignment with management priorities.
Coordinate sourcing of immune cells e.g. working with hospitals and blood banks to secure fresh donor
samples, or establishing relationships with companies that bank biological material.
Train and instruct junior scientists and lab technicians in experimental techniques. Assign lab
responsibilities to junior staff.
Act as technical lead on client calls and projects where scientific input is required e.g. initial client
pitches, written proposals, technical support inquiries, etc.
Write and review technical documentation including SOPs, product pages, and client reports.
Write research grants and oversee external research collaborations. Effectively manage a research
program between multiple project sites including technology transfer, planning, scheduling, invoicing, and reporting.
Write effectively for scientific and non-scientific audiences including peer-reviewed publications, white
papers, blog posts, press releases, marketing slide decks, and social media posts.
Salary and title is commensurate with experience.
Assertive team player with positive attitude and a sense of urgency to get things done. Must be a selfstarter, able to work independently, willing to take initiative and demonstrate efficient and effective time management.
Experience working with various primary immune cell types (e.g. NK cells, T cells, etc.)
Experience in designing and executing complex flow cytometry panels for the evaluation of various
immune cell types.
Experience in designing pre-clinical animal safety studies.
Working knowledge of cytokines and signaling pathways.
Excellent conceptual, strategic, analytical, problem solving, and organizational skills.
Excellent communication skills, both verbal and written, and the ability to interface effectively with all level of the organization. Strong communication skills with outside contract organizations, universities, and research institutions is required.
Fully versed with Microsoft Office software suite and project management software (e.g. MS Project).
Outstanding project management and coordination capabilities.
Spanish language fluency a plus, but not required.
Requires PhD Degree in immunology or related discipline.
1-2 years of experience (industry or postdoc) desired.Interested applicants should send their resume and cover letters to email@example.com or apply by visiting our website at https://www.akronbiotech.com/.
The EACRI, a division of the Providence Cancer Institute, at the Robert W. Franz Cancer Center invites applicants for full-time faculty positions in Immuno-oncology. The rank is open and will depend on the candidate’s research accomplishments. We are seeking energetic, creative and innovative individuals to complement a strong team of cancer immunologists. Applicants must hold a PhD and/or MD degree in immunology or related discipline. Applicants can be an established investigator with a strong record of published research in immunology and demonstrated success in garnering external funding or a junior faculty candidate with a clear vision of how to establish a funded, productive research laboratory. Competitive start-up funding is available. Additional information on our Institute can be found at www.franzcancer.org.
Apply now by going to https://bit.ly/2qcGnbs.
Apply now by going to https://bit.ly/2PWfdkr.
The Earle A. Chiles Research Institute (EACRI) at Providence Cancer Institute is looking for candidates to participate in an Immuno-Oncology Fellowship program. The immuno-oncology fellowship will provide advanced, supplemental training in the field of immuno-oncology, but is not intended to replace accredited fellowship training in oncology. The fellowship is ideal for recent medical/surgical oncology fellowship graduates, or internal medicine/surgery residency graduates who wish to pursue formal sub-specialty training in medical/surgical oncology after one year of intensive immuno-oncology training and research. To be eligible, a fellow must have completed at least one year of residency training in a related field (ex. medicine, surgery, or pathology). Candidates should be proficient in general immunology, but are not required to have previous formalized training in tumor immunology. The fellowship will run July 1, 2019-June 30, 2020.
Interested candidates should forward their CV to firstname.lastname@example.org.
Rush University Medical Center invites applications for The Robert E. and Emily H. King Endowed Professor of Cancer Research in the Department of Internal Medicine, Division of Hematology, Oncology and Cell Therapy. Rush is seeking a Physician Scientist focused on immunotherapy in the treatment of lymphoma and hematologic cancers. The successful candidate will have a demonstrated history of grant funding and an established reputation in the field. In addition, they are Board Certified/Board Eligible and incoming at the associate or professor level. The predominant criteria include: a major commitment to research and scholarly activity that advances the field of medicine, teaching, excellence in clinical care, and institutional service appropriate to the programmatic need the individual is expected to fulfill.
The vision for The Robert E. and Emily H. King Cancer Immunotherapy Research Program is to develop the next generation of cellular and immunologic treatments for hematologic malignancies, setting its sights initially on lymphoma, leukemia, and myeloma. The central component of the King Cancer Immunotherapy Research Program is the endowed professorship that will support cancer research at Rush in perpetuity. The endowment provides support for laboratory staff and equipment.
Rush University Medical Center is consistently ranked as one of the nation’s top hospitals by U.S. News & World Report. Rush is ranked in 7 of 16 categories in U.S. News & World Report's 2018-2019 "America's Best Hospitals" issue, and is one of the two top-ranked hospitals in Illinois overall. Rush was one of four hospitals in the country that the American Hospital Association honored for equity of care in June of 2018. Rush was the first hospital in Illinois serving adults and children to receive Magnet status – the highest honor in nursing – and the first in Illinois to earn a fourth four-year designation. Rush has been ranked among the country's top 100 hospitals — and 15 major teaching hospitals — four times by Truven Health Analytics, a leading provider of health care data and analytics. Rush is located short distances from transportation centers, sports facilities, and residential/shopping neighborhoods.
Interested candidates, please address your CV and cover letter to:
Timothy M. Kuzel, MD, FACP
The Samuel G. Taylor III, MD, Professor of Oncology
Chief, Division of Hematology, Oncology and Cell Therapy
Rush University Medical Center
via email to Rose Sprinkle, Manager, Faculty Recruitment at Rose_Sprinkle@rush.edu
Rush is an equal opportunity / Affirmative Action employer
The Mayo Clinic Department of Immunology in Scottsdale, Arizona is seeking an exceptional early- to mid- career Scientist with an interest in the study of cancer immunology and/or immunotherapy.
The successful candidate will study molecular and cellular mechanisms of the immune response to cancer and lead an independent and nationally/internationally-recognized research program. This person will hold academic rank at Mayo Clinic commensurate with experience and qualifications.
The ideal candidate will be a laboratory-based investigator whose research program and interests innovatively impact the field of cancer immunotherapy. Specific areas of interest include innate and adaptive immunity to cancer, and cancer immunotherapy (checkpoint blockade, vaccine or T cell transfer). Faculty will be expected to work collaboratively with colleagues and may align with one or more institutional centers (e.g., biomedical discovery, cancer, individualized medicine, regenerative medicine).
Candidates holding a doctoral degree (PhD, MD/PhD, or MD) at all levels of academic rank will be considered for this faculty position. Junior investigators should have a strong publication record and evidence of successful competition for external funding is preferred. Senior candidates must have a strong publication record and history of NIH- or equivalent extramural funding. The selected individual is expected to develop and/ or maintain a nationally and internationally recognized extramurally funded research program. Several collaborative and translational opportunities exist, such as participation in NCI Specialized Programs of Research Excellence (SPORE) grants, integrating all three Mayo sites (AZ, MN, and FL) and are strongly encouraged and supported. Mayo Clinic offers a highly competitive compensation package with sustained intramural salary support, outstanding laboratory facilities, capital equipment funding, technical and computational resources, and exceptional benefits.
MAYO CLINIC is ranked number one overall nation-wide as well as in more specialties than any other hospital in the nation for 2018-2019 by the U.S. News and World Report. We are an integrated, multidisciplinary academic medical center with an NCI-sponsored Comprehensive Cancer Center, and programs in medical education and research that span across three group practice sites. We support a vibrant research enterprise, with programs in basic, translational, clinical, and population sciences. In 2018, the institution received nearly $450 million in extramural research awards, supplemented with over $304 million of institutional support.
CLICK HERE to learn more and apply.
Applications should include a cover letter, CV, and a statement of research interests.
Mayo Foundation is an affirmative action and equal opportunity educator and employer. Post offer/pre-employment drug screening is required. ©2018 Mayo Foundation for Medical Education and Research.
A highly motivated and hardworking individual is sought to join the Laboratory of Antitumor T-cell Response (Dr. Eric Tran) as a Postdoctoral fellow at the Earle A. Chiles Research Institute (EACRI) at Providence Cancer Institute. www.franzcancer.org
The major goal of this lab is to develop new and more effective T-cell transfer immunotherapies to treat patients with metastatic epithelial cancers. Current projects include: 1) studying the immunobiology of the antitumor T-cell response in the microenvironment of human epithelial tumors with a focus on tumor antigen specificity and biological pathways perturbed in antitumor tumor-infiltrating T cells; 2) investigating strategies to broaden the antitumor T-cell response against human epithelial cancers; and 3) developing and evaluating novel gene engineering strategies to enhance the function of T cells for adoptive immunotherapy.
To find more information and to apply go to:
The Targeted Immunotherapy (TI) group within the Targeted Therapeutics Discovery (TTD) department has an opening for an enthusiastic, inquisitive, and creative cancer immunologist. The successful applicant will play a fundamental role in the implementation of TTD/TI strategy in the discovery and development of T cell bispecifics/multispecifics for immune cell retargeting and immune modulation. The incumbent will serve as a project leader applying their cancer immunology expertise to manage the scientific & strategic needs of the programs. Experience investigating mechanisms regulating T cell mediated immune responses and resistance mechanisms to redirected T cell therapies or immunotherapies is a significant plus. The successful candidate will have opportunities to propose/establish immune cell retargeting research projects and he/she is expected to collaborate with other program leaders and partner lines. The successful candidate will demonstrate a proven track record of scientific productivity as evidenced by first author publications in prominent journals. The candidate will demonstrate his/her ability to participate in a highly matrixed and innovative research environment. The successful applicant will be able to translate basic research findings into therapeutic strategies. The individual will be expected to participate in strategic discussions with department leadership. He/She will manage their own time to meet agreed targets, will develop plans for their own projects (timelines, work plans, deliverables) and will take a proactive role in their personal growth and scientific development.
Additional Job Description
Other Job Details:
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
Interested candidates please apply at:
The successful candidate will play a key role in building state of the art high throughput B cell cloning and sequencing pipeline in the cell-based antibody discovery group. The incumbent will collaborate with scientists within the organization to actively improve and drive therapeutic antibody discovery efforts by developing and employing state of the art B cell repertoire analysis and sequencing technologies. She/He will also participate in driving strategies and developing innovative technologies around cell-based therapeutic antibody discovery to enable deep antibody repertoire screening from immunized hosts. Primary responsibilities include but not limited to:
Memorial Sloan Kettering Cancer Center is seeking a Research Fellow (Pathology) to join our team. Under supervision of the group leader, the Research Fellow will provide support to research at the Center by assisting in the design, development, and implementation of imaging, deep learning and multi-modality projects in pathology.
To apply, please send a cover letter and resume/ CV to Christina M. Virgo, Esq. at email@example.com.
Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products — Imbruvica®, Venclexta™, and Empliciti™ — and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer.
AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and small-molecule technologies to discover and develop novel cancer treatments. This position will be based at Stemcentrx, AbbVie's South San Francisco, CA location.
Director/Senior Director of Cancer Biology will expand, strengthen and strategically lead a research department at the forefront of cancer biology. The successful candidate will be responsible for championing the future scientific vision and executing the scientific strategy that delivers compelling opportunities to the AbbVie pipeline. This role will be responsible for driving the science and research focused on achieving a deep understanding of tumor biology in the context of multiple technology platforms that can be translated into novel breakthrough therapies. Reporting to the Head of Research at AbbVie Stemcentrx, this position will play a key role on our Research Leadership Team, setting scientific strategy and contributing to successfully achieving cross-functional research goals through collaboration with other internal discovery research functions across sites. Additionally, the Head of Cancer Biology will work collaboratively with our Clinical and Development
Science Organizations, as well as represent Cancer Biology to Core Development Teams.
The ideal candidate should have a strong background in cancer biology and drug discovery, and a track-record of identifying and progressing novel concepts to clinical candidates. As a creative scientist and a critical thinker, this leader should have a stellar record in oncology research, preferably in solid tumors and in an industry setting. As a skilled organizational leader, this individual should be an efficient and accountable manager, an effective team builder and a productive collaborator who will provide strong organizational, technological and scientific leadership to early research, preclinical pipeline programs and platforms, and in support of clinical assets. This person will draw from past team leadership experience to develop the Cancer Biology team and guide the team to accomplish goals through superior performance.
Key Responsibilities Include:
* As the leader for cancer biology efforts, this role will play a substantial strategic role in guiding the scientific direction of research and pipeline programs at AbbVie Stemcentrx, and contribute new ideas to the research platform.
* As a member of the Research Leadership Team, develop and implement Discovery Strategy for AbbVie Stemcentrx.
* Propagate a development-oriented culture and champion the growth of a talented and aspirational team of cancer biologists. Develop and empower talent within the department.
* Identify, engage, and ensure the success of research collaboration across AbbVie’s global R&D network and the external scientific community.
* Maintain high-functioning and synergistic cross-functional relationships across the AbbVie discovery organization.
* Keep up-to-date with the latest scientific advancements (e.g. competitive landscape, new technologies and partnerships) and be well informed about emerging trends in oncology research and development to deliver the next generation of oncology discovery concepts.
* Work with the Research Leadership Team to allocate resources to ensure timely achievement of aggressive pipeline and technology goals.
* Set departmental scientific and business goals and manage people, resources, financial budget and other administrative functions.
* Develop and guide the structure of the Cancer Biology team in order to assure optimal efficiency, teamwork, and utilization of resources.
* Provide day-to-day scientific, technical and organizational leadership for the research teams and manage a portfolio of discovery projects to achieve scientific and operational excellence.
* Promote and foster a science-driven, goal-oriented culture with innovation, accountability, transparency, empowerment and agility.
* PhD in Life Sciences or equivalent with a minimum of 12 years of relevant industrial/academic experience in oncology positions of increasing responsibility.
* Demonstrated expertise in drug discovery from early research through IND-filing and translational science. Experience in progressing multiple pre-clinical candidates to IND approval is preferred.
* Experience in leading a high performing, mid-sized biology/drug discovery group of > 15 people in a biotechnology or pharmaceutical company. Proven record in developing people and fostering creativity, productivity, accountability and execution with a sense of urgency.
* Experience in both a small and large company settings is preferred.
* Demonstrated excellence in strategic planning and project leadership. Decisive problem solver with ability to balance creativity, innovation and probability of success.
* Proven scientific leadership with a track record of scientific innovation and accomplishment in disease biology research and oncology target discovery as evidenced by quality and quantity of publications, patents and conference presentations.
* Track record of developing efficient discovery processes and leading cross-functional team collaborations, including managing relationships with internal AbbVie discovery teams, academic collaborators and CROs.
* Self-starter with strong scientific curiosity and rigor, excellent interpersonal and analytic skills, high ethical standards and outstanding written and verbal communication skills.
Equal Opportunity Employer Minorities/Women/Veterans/Disabled
URL for your website or original job posting:
The role of a Principal Scientist is responsible for the overall conduct of studies in different immune-therapeutic area, overseeing experimental testing design, as well as formulating conclusions and recommendations for next steps. The incumbent has the ability to present Caprion capabilities to clients in a compelling way demonstrating value and differentiation as support function to Business Development activities as well as presentation of results to Sponsor and scientific meetings. The incumbent is ensuring that the timelines and milestones of a study are met by proactively assessing foreseeing challenges, assessing impact of deviations and overall quality of the study conduct.
Oversees the planning and progress of studies and projects under her/his responsibility;
Designs and prepares detailed study-specific work plans and support documentation for IM protocols and assays; discusses with management and obtains approval as appropriate;
Participates in the development of new in vitro assays as per client needs, including the assay qualification and validation phase;
Instructs laboratory personnel (e.g. research assistants and technicians) assigned to her/his projects;
Ensures that projects are conducted as per established timelines and delays are communicated in a proactive manner to clients with action plan to minimize the delays;
Identifies resource constraints and inefficiencies and works with management to resolve;
Prepares preliminary and final reports;
Ensures that all study-related data is appropriately maintained and archived;
Participates in the preparation of presentations and publications in collaboration with clients when possible;
Interacts regularly with clients, clinical sites and Caprion management to address project issues in a timely manner and to the satisfaction of the client. Documents study-related interactions and communications properly;
Actively participates in the preparation and conduct of audits for clients or regulatory bodies.
Ph.D. or equivalent training in life sciences, preferably in immunology, virology, microbiology or molecular biology.
Experience and Skills Required
A minimum of 5 years experience in an equivalent position in the industry;
Knowledge of modern immunology and kept abreast with current literature, IM methodologies and clinical trial design and regulations;
Knowledge and experience with flow cytometry techniques and its generic applications in the field of IM including testing design as well as handling complex data set of multi-color panels;
Knowledge of cell-based assays to monitor adaptive and innate immune responses;
Experience working with FlowJo, Pestle, Spice, Prism and Excel
Knowledge and understanding of GLP regulations and other regulatory guidelines sufficient to carry out GLP studies;
Experience in project management;
Experience with client management;
Strong communication ability;
Bilingual French and English (written & spoken).
Approaches work methodically and systematically;
Establishes priorities from among a number of demands;
Demonstrates and applies advanced level of understanding and analytical skills to interpret data and draw conclusions within the project goals;
Critical and creative thinker;
Communicates clearly and confidently and has excellent interpersonal skills;
Skilled at working in a fast-paced and multi-tasking environment.
Must be willing to perform duties or supervise activities in Bio Safety Level (BSL) 1 or 2 facilities where biological samples may be either naturally or experimentally infected with potentially hazardous viruses such as HIV, HCV, or CMV.
Interested candidates, the following link provides more details:
Email address for applicants: firstname.lastname@example.org
Kleo Pharmaceuticals is an emerging company at the forefront of synthetic organic chemistry and immunology. We are passionate about developing new, innovative small molecule immunotherapies to treat patients with cancer as well as other life-threatening diseases. Our Headquarters is located adjacent to Yale University in the vibrant city of New Haven, CT.
Description of the Role
We are seeking a highly motivated scientist and team player to lead our Cancer Immunology group and make major scientific contributions to advance our product pipeline. This individual will lead research team efforts and develop the strategies, technologies, and procedures to achieve important milestones in program development.
This position will incorporate a mixture of management and laboratory benchwork responsibilities. Accordingly, our ideal candidate will have proficiency in a wide range of laboratory techniques–especially assays using human and/or mouse immune cells, flow cytometry, ELISA, mammalian cell culture. Experience with antibodies and in vivo tumor models is highly desirable. Experience with cutting-edge techniques and technologies in your field is a plus. Immuno-oncology drug development experiment is essential.
Our ideal candidate may be working in either an industrial or an academic environment, but will possess a strong scientific research background and managerial experience. If you are passionate about advancing healthcare and this position is in agreement with your career goals, we would love to hear from you. A relocation package is available for qualified applicants and based upon level of work experience.
PhD in Immunology, Cell Biology, Cancer Research, or related field
5+ years of additional post-graduate and/or pharmaceutical experience in immunology, oncology and/or cell biology is required
Demonstrated record of scientific achievement and innovation (i.e. strong publication record or drug development portfolio)
Robust research experience in immunology assay development using multiple approaches (ie ADCC/CDC assays, FACS, ELISA, other) is essential
Immuno-oncology assay development experience, in vivo tumor models, and as well as a desire to continue in a laboratory-focused role
Proficiency in molecular biology techniques including cloning, transfection, PCR, qPCR is required
Capacity to thrive in a competitive, multi-disciplinary environment
Interested applicants may submit resumes to email@example.com
MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health and help fight and cure disease. As a Principal Scientist in Oncology Translational Medicine in Gaithersburg, MD you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.
We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it. We’re pioneering innovative research and exploring novel pathways across key therapeutic areas including oncology, respiratory, inflammation and autoimmunity, cardiovascular and metabolic disease, and infection and vaccines. And we’re industry-leading in immunology, protein engineering and translational science. We offer a unique and strong collaborative network as part of the AstraZeneca family, as together we explore synergies between small and large molecules.
MedImmune has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.
An attractive relocation package is available for non-local candidates.
Main Duties and Responsibilities:
We are seeking a dynamic thought leader in oncology translational medicine to support Medimmune’s growing pipeline of antibody drug conjugates in our Gaithersburg, MD headquarters. The Principal Scientist will provide exceptional scientific and strategic leadership to understand molecular heterogeneity of disease with a focus both on solid tumors and hematology/oncology and will apply this knowledge to the development of biologics at MedImmune.
The Principal Scientist will work with a team of translational medicine leaders, lab-enabled scientists and bioinformatics analysts to mine genomic and proteomic data from internal and external collaborations and clinical trials. The individual will help design, execute, and analyze biomarker data from clinical studies and have a strong background in development of biologics in oncology. An understanding of clinical trial design, regulatory processes, proof-of-concept studies, diagnostics, and biomarkers is required. The Principal Scientist will hold a leadership role on one or more Product Development Teams and in that capacity will focus on developing testable personalized healthcare strategies requiring analysis of research, translational and clinical data. The expected output is high-quality, scientifically-based product development decisions to be communicated to key stakeholders.
This is a high-profile role requiring an individual with outstanding communication and leadership skills. Vital to this role is the ability to build strong relationships with stakeholders in Research, Clinical Development, Biostatistics and other functions within MedImmune/AstraZeneca and to work effectively with external academic collaborators. The individual must be viewed as a strong scientific and strategic leader who can work within a fast-paced organization to translate fundamental insights in the molecular heterogeneity of disease into targeted therapeutic and biomarker hypotheses that can be tested in clinical trials. Strong project management skills and experience with IND-enabling studies and developing clinical protocols are required. The successful candidate is expected to drive the publication of manuscripts in top-tier scientific, technical or medical journals thereby establishing Medimmune’s scientific leadership.
The preferred candidate will have experience in the design and implementation of biomarkers in clinical studies to support development of antibody drug conjugates in oncology.
Experience with predictive biomarkers and precision medicine approaches is highly desired.
Strong collaboration skills are required that enable effective leadership within product development and scientific teams. Must be highly effective in collaborating with external experts.
Must possess outstanding communication skills, both verbal and written, with the ability to deliver scientific information and proposals to audiences at all levels and functions.
This role requires an outstanding record of innovative contributions to translational sciences in oncology as evidenced by a strong publication record including publications in top-tier journals, inventorship on crucial patents/filings and congress presentations.
The successful candidate should be able to work effectively in a matrix team environment, as well as take ownership of multiple projects.
Organizational skills and demonstrated ability to perform quantitative analysis, graph and present data, write technical reports, and prepare biomarker protocols are required.
Experience developing clinical protocols and regulatory documents is highly desired.
The candidate will have demonstrated an ability to commit to goals and to deliver high quality results.
Experience mentoring and/or managing direct reports is a plus.
Education: PhD, MD/PhD, or MD degree in a relevant scientific field (e.g. molecular biology, immunology, cell signaling, bioinformatics).
A minimum of 12 years post-PhD/MD experience in an academic and/or industry setting.
Next Steps – Apply today!
To be considered for this exciting opportunity, please complete the full application on our website. If you know someone who would be a great fit, please share this posting with them.
MedImmune is an equal opportunity employer. MedImmune will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.
MedImmune is the worldwide biologics research and development arm of AstraZeneca. Here, you’ll have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world health and help fight and cure disease. As a Senior Director, Toxicology in Gaithersburg, MD you’ll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.
The Senior Director of toxicology with a focus on safety and translational sciences aspects of ADC drug development. This position will be reporting directly to the Vice President of Global Safety Assessment. An attractive relocation package is available for non-local candidates.
Responsible for the successful operation of activities of major significance (e.g., filing of discovery, mechanistic toxicology projects, INDs and BLAs) to the biologics safety assessment and translational sciences
Global Biologics R &D cross-functional strategic and advisory role as an Antibody Drug Conjugates thought leader
The position will provide strategic support and guidance on ADC safety-toxicology to all project toxicologists as well as other scientists in translational sciences/medicine functions.
Support activities will be on ensuring consistency in nonclinical strategy for early and late stage ADC projects. With respect to late stage projects (Phase II and beyond), focus will be on BLA and label writing, extractables & leachables, safety strategy, regulatory strategy and interactions and post-marketing activities.
Lead to advance the ADC pipeline from early discovery to clinical development, by developing and implementing consistent nonclinical PK/PD and safety strategies
Manages the ADC safety sciences and business strategies, plans and actions and uses broad scientific knowledge and experience to manage the outcomes and actions of a variety of projects across a toxicology functional area.
Responsible for implementing learnings from late stage projects into early stage projects, and for guiding and directing the global implementation of novel translational platforms (e.g. humanized mouse models) to assess ADC and IMT-C combination PK/PD and safety, with the aim to improve translational value and predictivity.
Education: Ph.D. /DVM/DVM-Ph.D. in relevant discipline of biological sciences with specialization in safety sciences with at least 15 years of experience in oncology drug development, including ADC projects
At least 15 years of post-Ph.D. experience with a minimum of 10 years’ experience in Biologics
Must have strong toxicology background (board certification in Toxicology is highly desirable) and drug development experience
The candidate must have a proven record in filing INDs, BLAs etc.
Must have a strong understanding of biologics drug development, oncology (e.g., immunotherapy of cancer), with specialization in ADCs
General Scope, Knowledge, and Qualifications:
Develops and leads Early discovery, early clinical and late stage and plans to advance numerous scientific opportunities.
Creates competitive and breakthrough strategies and plans.
Communicates a compelling vision and sense of purpose in ADCs
Responsible for the overall leadership and operational success of assigned functions, and for successfully integrating these activities with those of other major organizational segments.
Strong leadership and effective management skills
Innovative, creative and able to influence others in a positive manner
Strong communication, organizational and interpersonal skills to work matrix setting, manages projects and team members in a matrix environment.
Problem solving and organizational skills with attention to details related to drug development.
Strong team player and strong motivational skills.
Strong publication record in toxicology/pharmacology
Strong experience in MECHANISTIC AND MOLECULAR TOXICOLOGY of Small and Large Molecule drugs
Applies knowledge of current and future industry trends and how they will affect the business.
Knows the competition and how strategies and tactics work in the marketplace.
Demonstrates broad knowledge and perspective outside of own organizational segment.
Be part of a fast-paced, integrated and interactive research group exploring therapeutics for Oncology, Inflammation and Cancer Immunotherapy programs.
Designing, conducting, analyzing and reporting in vivo and in vitro studies.
Outstanding compensation and benefits. Apply at http://careers.amgen.com/ to job #R-63328.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
The H. Lee Moffitt Cancer and Research Institute is a modern facility in Tampa, Florida. We strive to be the leader in understanding in the complexity of cancer through team science and applying those insights for human benefits. Be part of the cure by joining Moffitt's team of 800 research faculty scientists, career staff scientists, postdocs, graduate students and support staff dedicated to cancer research.
The Research Scientist is a non-tenure track researcher who assumes the direct responsibility of conducting and performing experiments or directly overseeing experimentation as part of a research team under the general guidance of Dr. James Mulé.
Research is focused on experimental strategies to enhance immunotherapy in cancer patients using a variety of in vitro and in vivo immune cell and tumor assays as well as bioengineering strategies.
Opportunities for career advancement through attendance and presentations at nationals and international meetings
The Ideal Candidate:
Experienced scientist with knowledge in techniques and methodologies of Immunology
Familiarity and extensive experience with multi-color Flow cytometry
Experience with immune cell cultures, immunological assays, and processing tissues
Design, plan, and perform experiments with limited supervision
Attend and present work at scientific meetings and seminars
Report and disseminate knowledge gained in the laboratory through public presentation and manuscripts
Promote a collaborative environment within the laboratory and with outside collaborators
Provide supervision and guidance to other lab members with their ongoing projects
Credentials and Qualifications:
Minimum of a M.D. or Ph.D. in Biological Science or related field with three to five years of postdoctoral experience.
The person for the job should have the knowledge as specified by the Investigator.
How to Apply: Interested applicants should send a single PDF file that includes a cover letter summarizing their research training and accomplishments, a personal statement of scientific interests and goals, current CV with recent publications, and contact information for three references to Brittany Palermo at Brittany.Palermo@moffitt.org
We are seeking a talented postdoctoral fellow to conduct basic and translational research projects with the aim of improving anti-tumor immunity in the laboratory of Dr. James J. Mulé at the H Lee Moffitt Cancer Center in Tampa, FL. We have a number of exciting research projects available for both basic and translational work, with ample opportunity to develop additional research avenues in the fields of tumor infiltrating lymphocyte (TIL) therapy, chimeric antigen receptor T cell (CAR-T) therapy, impacting the tumor microenvironment, T cell trafficking, and the induction of tertiary lymph node structures.
Plan and conduct research experiments with limited guidance
Write and submit manuscripts for publication in peer-reviewed journals
Attend and present data at national conferences
Present project updates in department seminars and weekly meetings
Network and liaison with leaders in the biotech industry and with other prominent academic scientists.
The Ideal Candidate will have:
Documented success in research publications and scientific achievement
Established communication skills, and a functional use of the English language in scientific conversation
An established background in basic microbiology, immunology, and/or cancer biology
Experience or willingness to work in preclinical animal models
To organize, plan, and conduct scientific research encompassing one or more projects relating to anti-tumor immunotherapies
To diligently document all research activities
To analyze resulting research data
To create presentation and publication quality figures
To write and prepare scientific manuscripts for publication
To prepare and give scientific presentations
To maintain all necessary trainings and credentials required for relevant scientific research
Credentials and Qualifications:
MD or PhD in immunology, cancer biology, or related field
How to Apply: Interested applicants should send a single PDF file that includes a cover letter summarizing their research training and accomplishments, a personal statement of scientific interests and goals, current CV with recent publications, and contact information for three references to Brittany Palermo at Brittany.Palermo@moffitt.org
The University of Central Florida, College of Medicine is seeking applicants for a tenure or tenure track Assistant, Associate, or Full Professor position in the Department of Internal Medicine. The successful applicant will be an outstanding physician scientist who will conduct independent hematology or oncology research as well as practice clinically in collaboration with our community partners.
UCF is seeking a well-rounded candidate who has demonstrated research excellence and has experience participating in oncology care. The preferred candidate for this position will be serving as a PI on one or more active NIH RO1 or equivalent grants. The ideal candidate will have an interest in collaborating with existing faculty in any of the following areas: Metabolism, Genomics, Immunotherapy, Pediatric Oncology, Neuro-Oncology, and Hematology. The College of Medicine offers a state-of-the-art research infrastructure that includes well-equipped laboratories, robust core resources, advanced imaging equipment, and extensive small animal facilities.
Established in 2006, the UCF College of Medicine is an innovative and forward-looking medical school with a culture of collaboration and partnerships. As a part of a growing “Medical City” dedicated to innovation in health and wellness, the UCF College of Medicine campus has grown to an Academic Health Sciences Center that includes multiple health affairs disciplines, a state-of-the-art research center at the Burnett School of Biomedical Sciences, the fully accredited medical school, multiple clinical graduate medical education programs, UCF outpatient clinics, and the UCF Lake Nona Medical Center under construction. Nearby are the Orlando Veterans Affairs Medical Center, the Guidewell Innovation research incubator, the Nemours Children's Hospital, and the new UCF Lake Nona Cancer Center. Equal Employment Opportunity Employer As an equal opportunity/affirmative action employer, UCF encourages all qualified applicants to apply, including women, veterans, individuals with disabilities, and members of traditionally underrepresented populations. UCF's Equal Opportunity Statement can be viewed at:http://www.oie.ucf.edu/documents/PresidentsStatement.pdf. As a Florida public university, UCF makes all application materials and selection procedures available to the public upon request.
Candidates must have a M.D. or M.D./Ph.D. degree from an accredited school and have three years of experience in faculty level academic positions. Candidates must have demonstrated independent scholarly productivity in oncology research, based on a record of extramural funding success and publications in peer-reviewed journals. Board certification in an appropriate specialty is required, with eligibility for physician licensure in the state of Florida.
In order to be eligible for an appointment as a tenured associate or full professor of medicine upon hire, the successful candidate must have a demonstrated record of scholarly achievement, teaching experience and service commensurate with rank.
Preferences: The preferred candidate for this position will be serving as a PI on one or more active NIH RO1 or equivalent grants. The ideal candidate will have an interest in collaborating with existing faculty in any of the following areas: Metabolism, Genomics, Immunotherapy, Pediatric Oncology, Neuro-Oncology, and Hematology. Additional Application Materials Required:
All applicants must apply through www.jobswithucf.com. In addition to the online application, candidates must also submit a cover letter, a CV, a brief statement outlining their research interests and plan, and the contact information for three professional references, including capacity of the relationship.
NOTE: Please have all documents ready when applying so they can be attached at that time. Once the online submission process is finalized, the system does not allow applicants to submit additional documents at a later date.
Please contact Brittany Hofmann, Brittany.firstname.lastname@example.org, with questions about the position.
Apply Here: http://www.Click2Apply.net/dhhsmr7swvnd8dw9
The Department of Immunology at The University of Texas MD Anderson Cancer Center is seeking applications for a term tenure-track faculty position at any level. We are seeking highly motivated individuals with a strong interest in fundamental immunology research as it relates to cancer. Candidates should demonstrate a record of high-level publications and a history of or strong potential for peer-reviewed research funding. Innovative investigators with immunology experience are welcome to apply.
The position offers the opportunity for scientific and professional growth and development with an exciting and active group of scientists whose diverse research interests comprehensively span the field of immunology. Located in a 132,000 sq.ft. research building, the department hosts state-of-the-art flow cytometry, CyTOF, single-cell sequencing, two-photon imaging, transgenic and gene-targeting, protein expression, hybridoma, and histology facilities. Our faculty study cellular and molecular mechanisms of innate and adaptive immunity. MD Anderson offers excellent opportunities for collaboration with clinicians, allowing investigators to translate their fundamental research to the cancer problem.
Competitive start-up packages will be provided to successful candidates. Houston, home of the Texas Medical Center with a wealth of exciting basic and clinical research across 54 institutions, offers an affordable cosmopolitan living environment and is ranked as the most diverse major city in the United States.
Interested applicants should submit their cover letter, current curriculum vitae, research plan, and contact information for three references to:
The University of Texas MD Anderson Cancer Center
Attn: Misty Hajek
Research Department Administrator
7455 Fannin Street, Suite 3.2013
Houston, TX 77054
MD Anderson Cancer Center is an equal opportunity employer and does not discriminate on the basis of race, color, religion, age, national origin, sex, sexual orientation, gender identity/expression, disability, veteran status, genetic information, or any other basis protected by federal, state, or local laws, unless such distinction is required by law. All positions at The University of Texas MD Anderson Cancer Center are security sensitive and subject to examination of criminal history record information. Smoke-free and drug-free environment.
The National Cancer Institute (NCI) is seeking candidates with a medical degree and experience in cancer immunotherapy for the position of Supervisory Physician (GP-602-15), Branch Chief of the Immuno-Oncology Branch (IOB), Developmental Therapeutics Program (DTP), Division of Cancer Treatment and Diagnosis (DCTD).
The candidate will serve as a Supervisory Physician/Branch Chief directing the activities of the IOB (https://dtp.cancer.gov/organization/iob/default.htm) and will collaborate with investigators of the DTP (https://dtp.cancer.gov/). The candidate will manage and coordinate all functions of the branch including planning, designing and executing preclinical research and clinical development of immunotherapy agents through a cross-functional collaboration within DTP and DCTD. As a senior advisor to the Division Director and Institute Director, the candidate will set priorities for federal investment in the development of new methods, technologies, and treatment paradigms that integrate immunomodulation strategies into clinical studies. The candidate is expected to manage and coordinate a system of grants and contracts to discover, investigate, develop and bring to initial clinical trials novel immuno-oncology products.
This is a full-time government position. Compensation for this position will commensurate with the individual’s qualifications and experience as permitted within Federal government appointments. Individuals who apply must be U.S. citizens. The candidate should have a clinical background and training in immunology, medical oncology, hematology, pharmacology, clinical trials, and the development of investigational anti-cancer drugs. To apply to this position, please visit https://www.usajobs.gov vacancy number, NIH-NCI-DH-19-10314795. NCI will be accepting applications beginning on December 5, 2018.
Interested candidates should contact, Dr. Rosemarie Aurigemma at email@example.com or at (240) 276-5465. For application and qualification requirements, please contact Paulette Moore at firstname.lastname@example.org; 301-402-5057.
DHHS, NIH, and NCI are Equal Opportunity Employers
The Research Scientist is a non-tenure track researcher who assumes the direct responsibility of conducting and performing experiments or directly overseeing experimentation as part of a research team under the general guidance of Dr. Shari Pilon-Thomas.
Research is focused on strategies to enhance Tumor Infiltrating Lymphocyte (TIL) therapy in patients
Experience with T cell culture, immunological assays, and processing human blood cells
Provide supervision and guidance to other lab members with their ongoing projects
Interested parties should submit their cover letter and CV to Dr. Pilon-Thomas using the following contact information:
Moffitt Cancer Center
Attn: Shari Pilon-Thomas, PhD
12902 Magnolia Drive
SRB-3, Immunology Department
Tampa, FL 33612
Apply directly at the following link: https://bit.ly/2QSOa9P
AbbVie is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott Laboratories. The company's mission is to use its expertise, dedicated people and unique approach to innovation to develop and market advanced therapies that address some of the world's most complex and serious diseases. Together with its wholly-owned subsidiary, Pharmacyclics, AbbVie employs more than 29,000 people worldwide and markets medicines in more than 170 countries. At AbbVie, our vision is to be recognized as a biopharmaceutical company delivering a consistent stream of innovative medicines that solve serious health issues and have a remarkable impact on people’s lives.
To be successful, we need outstanding individuals willing to challenge themselves to find the best solutions for our patients. The AbbVie Postdoc program is one way we are doing just that.
Through our Postdoc program, we are hiring postdocs from key academic institutions for preferred areas of science in the U.S., while providing a unique opportunity for participants to build a solid career foundation in the pharmaceutical industry while building the AbbVie brand as an employer of choice for scientific talent. The program offers a balance of structured learning and work experience, with accessibility to high-level knowledge building across the drug development continuum to help participants understand how everything fits together and is put into practice. It also provides them with a chance to establish working relationships with some of the world’s most respected scientists and leaders in the industry. Participants in the Postdoc program play an integral part in our continued success and will help us to further grow as a leader in our industry. This assignment is expected to be two years, minimally, and no more than three years.
AbbVie is at the forefront of cancer research, discovering and developing the next generation of treatments to address unmet medical need for cancer patients. Our strong pipeline includes both small molecule and biologic therapeutic approaches with first in class agents that target multiple pathways central to the growth and survival of both solid and hematological malignancies.
We are seeking a highly motivated postdoctoral scientist with a proven track record of research accomplishments to join our growing cancer research organization. The scientist will join a team dedicated to identify and validate targets associated with immunogenic cell death pathways.
Champion efforts to apply functional genomic screening technologies and chemical probes to identify and validate targets associated with immunogenic cell death pathways
Develop and maintain appropriate in vitro assays to measure immunogenic cell death phenotypes
Investigate the biological pathways and cross talk between tolerogenic and immunogenic cell death while developing a publication-driven research program.
Communicate results to multi-disciplinary teams
Successful completion and defense of a PhD in Cancer Research, Immunology, or related field
Demonstrated record of scientific achievement (i.e. strong publication in a top tier peer review journal(s)
Extensive laboratory research experience and desire to continue in a laboratory focused role.
Demonstrated experience in immunology/oncology with a strong working knowledge of innate and adaptive immune cell biology and tumor/immune cell interactions
Ability to independently develop novel assays and cellular models for interrogation of immunogenic cell death
Proficiency in standard biochemical, cellular and molecular techniques
Ability to multitask and work with timelines
Ability to thrive in a fast paced, multi-disciplinary environment interacting with a diverse group of experts within or outside of scientific discipline.
Enthusiasm and passion for conducting creative scientific research
Work authorization in the United States
Effective communication and teamwork skills
Excellent problem-solving skills including critical and analytical thinking.
Demonstrated scientific writing skills and strong verbal communication skills.
Proven track record of teamwork, adaptability, innovation, initiative, and integrity.
Global mindset to thrive in a diverse culture and environment. Demonstrated scientific writing skills and strong verbal communication skills.
Global mindset to thrive in a diverse culture and environment.
Key Leadership Competencies:
Builds strong relationships with peers and cross functionally with partners outside of the immediate team to enable higher performance
Learns fast, grasps the "essence" and can change course quickly where indicated
Raises the bar and is never satisfied with the status quo
Creates a learning environment, open to suggestions and experimentation to drive the science in the field of interest
Embraces the ideas of others, nurtures innovation and manages innovation to reality
For further information on the company and its people, portfolio and commitments, please visit www.abbvie.com. Follow @abbvie on Twitter or view careers on our Facebook or LinkedIn page. Equal Opportunity Employer Minorities/Women/Veterans/Disabled
Tel: +1 414 271 2456 | Fax: +1 414 276 3349 | Email: email@example.com